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This study ispart of a larger body of work suggesting that in a varietyof preclinical models, metabotropic glutamate receptor(mGluR1 and mGluR5) antagonists, as well as agonists atalpha-amino-3-hydroxy-5-methylisoxazole-4-propionicacid (AMPA) receptors, have antidepressant-like activ-ity. This comparison resulted in thetest concordance being slightly lower, with 57% concordantresults for male rats, 64% for female rats, 39% for male mice,and 33% for female mice.
Role of rifampin against Propionibacteriumacnes biofilm in vitro and in an experimental foreign-body infection model.
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However, although they mayprovide promising and interesting data regardinglung and respiratory physiology, there is not datashowing that their use changes patient outcomes(Terragni et al.
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